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Canada, a new market for medicinal African wild mango seeds

  • Canada, a new market for medicinal African wild mango seeds?

    by Market Insider

    Monday, 01 Sep. 2014

    African wild mango (Irvingia gabonensis) seed (a.k.a. kernel) is a product of African biodiversity. According to PROTA (Plant Resources of Tropical Africa), the trees are indigenous to the humid forest zone of the Gulf of Guinea from western Nigeria east to the Central African Republic, and south to Angola and the westernmost part of Democratic Republic of Congo; it also occurs in São Tomé et Príncipe.

    There is also commercial cultivation of African wild mango trees in southern Nigeria and southern Cameroon. The seeds are widely and extensively traded domestically but also exported to Europe and beyond. PROTA reports that Cameroon is probably the main exporter with a combined export trade of the fruit kernels (of two species; Irvingia gabonensis and Irvingia wombolu) of 107 t annually valued at about US$ 260,000.

    The World Agroforestry Centre of Kenya states that, in southern Cameroon, wild African mango seed could be described as the most important, legal, non-timber forest product from the area.

    At the end of July 2014, the Canadian government’s 'Natural and Non-prescription Health Products Directorate' (NNHPD) published a Wild African Mango monograph that is intended to serve as a guide to industry for the preparation of Product License Applications (PLAs) and labels for natural health product market authorization.

    Now in Canada, companies wanting to market finished products that contain Wild African Mango seed as an active ingredient may be granted marketing authorization and permitted the following claim statements for labeling:

    §  Could be a complement to a healthy lifestyle that incorporates a calorie-reduced diet and regular physical activity for individuals involved in a weight management program;  

    §  Helps support healthy cholesterol levels/Helps support cardiovascular health by reducing total and LDL cholesterol;

    §  Helps support healthy glucose levels; and/or

    §  Provides antioxidants

    Additionally, the NNHPD is permitting the use of 'Irvingia Gabonensis Kernel Butter' as a non-medicinal component of licensed topical application Natural Health Products (NHPs) when used in formulations as an occlusive skin-conditioning agent (ingredients which retard the evaporation of water from the skin surface).

    Although the Canadian labeling standards monograph is brand new, at the time of this writing (August 2014), there were already 71 licensed NHPs in the Canadian market containing extracts or preparations of African wild mango seed as an active ingredient. Prior to the establishment of the monograph, the applicant companies submitted their own proposed indications for use based on their own efficacy evidence for their product.

    The establishment of a government issued compendial monograph for African wild mango seed paves the way for a much faster and streamlined process for gaining market access in Canada.

    Image source: cover of Health Canada draft monograph available at: http://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq.do?atid=irvingia.gabonensis&lang=eng 


    Health Canada Natural and Non-prescription Health Products Directorate (NNHPD). Drugs and Health Products: African Wild Mango. Ottawa, Ontario: NNHPD. 23 July 2014. Available at: http://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq.do?atid=irvingia.gabonensis&lang=eng Accessed 29 August 2014.

    Orwa C, Mutua A , Kindt R , Jamnadass R, Simons A. 2009. Irvingia gabonensis. In: Agroforestree Database:a tree reference and selection guide version 4.0. Available at: http://www.worldagroforestry.org/treedb2/AFTPDFS/Irvingia_gabonensis.pdf Accessed 29 August 2014.

    Tchoundjeu, Z. & Atangana, A.R., 2007. Irvingia gabonensis (Aubry-Lecomte ex O’Rorke) Baill. [Internet] Record from PROTA4U. Lemmens, R.H.M.J., Louppe, D. & Oteng-Amoako, A.A. (Editors). PROTA (Plant Resources of Tropical Africa / Ressources végétales de l’Afrique tropicale), Wageningen, Netherlands. <http://www.prota4u.org/search.asp>. Accessed 29 August 2014.

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